[Article] Time-frequency characterization of cerebral hemodynamics of migraine sufferers as assessed by NIRS signals

[Article] Time-frequency characterization of cerebral hemodynamics of migraine sufferers as assessed by NIRS signals characterization of cerebral hemodynamics of migraine sufferers as assessed by NIRS signals. Porto, the institutional repository of the Politecnico di Torino, is provided by the University Library and the IT-Services. The aim is to enable open access to all the world. Please share with us how this access benefits you. Your story matters. Near-infrared spectroscopy (NIRS) is a noninvasive system for the real-time monitoring of the concentration of oxygenated (O 2 Hb) and reduced (HHb) hemoglobin in the brain cortex. O 2 Hb and HHb concentrations vary in response to cerebral autoregulation. Sixty-eight women (14 migraineurs without aura, 49 migraineurs with aura, and 5 controls) performed breath-holding and hyperventilation during NIRS recordings. Signals were processed using the Choi-Williams time-frequency transform in order to measure the power variation of the very-low frequencies (VLF: 20–40 mHz) and of the low frequencies (LF: 40–140 mHz). Results showed that migraineurs without aura present different LF and VLF power levels than controls and migraineurs with aura. The accurate power measurement of the time-frequency analysis allowed for the discrimination of the subjects' hemodynamic patterns. The time-frequency analysis of NIRS signals can be used in clinical practice to assess cerebral hemodynamics.